Solgar Glycine 500mg 100 Caps, Non GMO, Gluten Free, Vegan

Glycine is a non-essential amino acid synthesized in the body through various complex pathways involving Threonine Serine Hydroxyproline and Choline metabolism. It is involved in the synthesis of purines porphyrins creatine and glyoxylic acid and is also a biochemical constituent of the tripeptide glutathione. Glycine is also essential for the synthesis of bile and nucleic acids and it is used in many commercial gastric antacid preparations. It is important in the central nervous system where it acts as one of the main inhibitory neurotransmitters. Although high amounts of Proline and 4-hydroxyproline are found in collagen (important for skin and connective tissue) almost 1/3 rd is comprised of Glycine. High amounts of Glycine are found in gelatin which is a denatured collagen. Low plasma levels of Glycine are noted in hypoglycemics those with viral infections and fevers CFS (Chronic Fatigue Syndrome) and anemia. A metabolic disorder causing excessive levels of Glycine in the spinal fluid is responsible for Non-Ketotic Hyperglycemia or Rett Syndrome which has symptoms of autism.